Just registered to do some reporting.
Uncharted 2 did not run at all on 2.08.04 (I could get my hands on the game just now, so no experience with previous versions). It gave a moving corrupted graphic which is that spinning dagger and stayed like that forever.
I tried running the game via Gaia Manager 2.07 and it worked like charm without any issues. So I thought this might need some looking into -I'm not sure.
Thanks for the great tool, btw.